Varicella-Zoster Virus and Herpes Simplex Virus DFA with Reflex to Varicella-Zoster Virus Culture and Herpes Simplex Virus Culture
Ordering Recommendation
Rapid diagnostic test with reflex to culture. May help to determine whether a lesion is due to varicella-zoster virus (VZV) or herpes simplex virus (HSV).
New York DOH Approval Status
Specimen Required
Collect vesicle specimen during first 3 days of rash.
Vesicle fluid or swab, tissue, or skin scrapings. Swab should be rolled in base of fresh vesicle to obtain cells.
Immediately transfer specimen to viral transport media (ARUP Supply #12884) and refrigerate (extremely temperature sensitive). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at 800-522-2787.
Refrigerated.
Bone marrow, CSF, or whole blood. Calcium alginate, eSwab, dry or wood swabs.
Specimen source preferred.
Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: Unacceptable
Methodology
Direct Fluorescent Antibody (DFA) Stain/Cell Culture
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Negative
Interpretive Data
Modified FDA
Note
If DFA results are negative or inadequate, then VZV and HSV cultures will be added. Additional charges apply.
Sensitivity of DFA methodology is dependent upon adequacy of the specimen. If the specimen contains fewer than 20 cells, then DFA results will be reported as "inadequate."
Hotline History
CPT Codes
87290; 87274; 87273; if reflexed, add 87252; 87254; 87255
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0060302 | Varicella-Zoster Virus, DFA with Reflex | 5882-6 |
0060303 | Herpes Simplex Virus 1, DFA | 5846-1 |
0060304 | Herpes Simplex Virus 2, DFA | 5849-5 |
0060336 | VZV HSVFAC Source | 31208-2 |
Aliases
- Herpes Culture
- Herpes Simplex Viral Culture
- Herpes Simplex Virus Antigen Detection, DFA.
- Herpes Zoster
- Herpes Zoster Antigen Detection & Culture
- Herpes Zoster Antigen Detection and Culture
- HSV 1 and HSV 2
- Varicella Zoster Virus
- Varicella Zoster Virus Antigen Detection
- VZV
- VZV Antigen Detection and Culture